Background:

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family| mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.

Classification:

Primary antibody

Alternative names:

MSH5

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human MSH5

Concentration:

1 mg/ml

Molecular weight:

91740

Applications:

WB

Storage:

-20°C for 1 year

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