Background:

This gene encodes a preproprotein that is proteolytically processed to generate two protein products| megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants| at least one of which encodes an isoform that is proteolytically processed.

Classification:

Primary antibody

Alternative names:

Mesothelin; Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; Megakaryocyte-potentiating factor; MPF; Mesothelin; cleaved form;

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human Mesothelin

Concentration:

1 mg/ml

Molecular weight:

69300

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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