Background:

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members| which include Mad| Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation| differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

MAX ;Phospho Ser11; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human MAX (Phospho Ser11)

Concentration:

1 mg/ml

Molecular weight:

17600

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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