Background:

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue| encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity| suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family.

Classification:

Primary antibody

Alternative names:

LOXL4

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human LOXL4

Concentration:

1 mg/ml

Molecular weight:

83160

Applications:

WB

Storage:

-20°C for 1 year

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