Background:

This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues| which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide| glycosidase domain| transmembrane domain| and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis| and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

LCTL; Lactase-like protein; Klotho/lactase-phlorizin hydrolase-related protein

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human LCTL

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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