Background:

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Classification:

Primary antibody

Alternative names:

Jak3 ;Tyr980/981 ; Tyrosine-protein kinase JAK3; EC 2.7.10.2; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phosho peptide around human Jak3 (Tyr980 and 981)

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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