Background:

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection| the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.|Belongs to the integrin alpha chain family.|Contains 7 FG-GAP repeats.|subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.|

Classification:

Primary antibody

Alternative names:

ITGA5 ;heavy chain; Cleaved-Arg894; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain;

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ITGA5 (heavy chain| Cleaved-Arg894)

Concentration:

1 mg/ml

Molecular weight:

115390

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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