Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.

Classification:

Primary antibody

Alternative names:

ITGA3 ;heavy chain; Cleaved-Phe33; Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD antigen CD49c; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain;

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ITGA3 (heavy chain| Cleaved-Phe33)

Concentration:

1 mg/ml

Molecular weight:

115610

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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