Background:

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al.| 2003

Classification:

Primary antibody

Alternative names:

HSH2D; Hematopoietic SH2 domain-containing protein; Hematopoietic SH2 protein; Adaptor in lymphocytes of unknown function X

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human HSH2D

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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