Background:

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions| and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors| inositol 1|4|5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling| T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

HOME3

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human HOME3

Concentration:

1 mg/ml

Molecular weight:

39710

Applications:

WB

Storage:

-20°C for 1 year

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