Background:

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4| originally named CHIF for channel-inducing factor| has been shown to modulate the properties of the Na|K-ATPase| as has FXYD2| also known as the gamma subunit of the Na|K-ATPase| and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2)| with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.

Classification:

Primary antibody

Alternative names:

FXYD4

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human FXYD4

Concentration:

1 mg/ml

Molecular weight:

9790

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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