Background:

The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7| a protein that induces mitotic arrest| by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family| such as FBXL18| are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box| and they interact with ubiquitination targets through other protein interaction domains.

Classification:

Primary antibody

Alternative names:

FXL18

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human FXL18

Concentration:

1 mg/ml

Molecular weight:

88550

Applications:

WB

Storage:

-20°C for 1 year

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