Background:

This gene encodes one of three related filamin genes| specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain| a C-terminal self-association domain| and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

FLNC

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human FLNC

Concentration:

1 mg/ml

Molecular weight:

299750

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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