Background:

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif| the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact| F-box proteins are one of the four subunits of ubiquitin protein ligases| called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats| leucine-rich repeats| or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

Classification:

Primary antibody

Alternative names:

FBXW2

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human FBXW2

Concentration:

1 mg/ml

Molecular weight:

49940

Applications:

WB

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

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