Background:

This gene encodes a protein with an N-terminal filamin-binding domain| a central proline-rich domain| and| multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion| cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

FBLI1

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human FBLI1

Concentration:

1 mg/ml

Molecular weight:

41030

Applications:

WB

Storage:

-20°C for 1 year

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