Background:

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product| which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2.

Classification:

Primary antibody

Alternative names:

EXOC6

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human EXOC6

Concentration:

1 mg/ml

Molecular weight:

88440

Applications:

WB

Storage:

-20°C for 1 year

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