Background:

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This gene is expressed in several tissues| particularly in colon| trachea and in brain| and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported| but the biological validity and/or full-length nature of some variants have not been determined.

Classification:

Primary antibody

Alternative names:

EST3; Carboxylesterase 3; EC 3.1.1.1; Liver carboxylesterase 31 homolog

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human EST3

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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