Background:

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits| alpha| beta| and gamma| with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP| which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

eIF2B ;Phospho Ser67; Eukaryotic translation initiation factor 2 subunit 2; Eukaryotic translation initiation factor 2 subunit beta; eIF-2-beta

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human eIF2B (Phospho Ser67)

Concentration:

1 mg/ml

Molecular weight:

36630

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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