Background:

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region)| which spans 2.5 Mb on 21q22.2| has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome| including morphological features| hypotonia| and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

Classification:

Primary antibody

Alternative names:

DSCR3

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DSCR3

Concentration:

1 mg/ml

Molecular weight:

32670

Applications:

WB

Storage:

-20°C for 1 year

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