Background:

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated| cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian| prostate| glioma| and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described| but only one has been fully characterized.

Classification:

Primary antibody

Alternative names:

DOCK4

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DOCK4

Concentration:

1 mg/ml

Molecular weight:

216260

Applications:

WB

Storage:

-20°C for 1 year

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