Background:

Catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).|cofactor:Binds 2 magnesium ions per subunit.|Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.|Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.|Belongs to the DNA polymerase type-X family.|subunit:Monomer.|

Classification:

Primary antibody

Alternative names:

DNA pol β ;Acetyl Lys72; DNA polymerase beta; EC 2.7.7.7; EC 4.2.99.-

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DNA pol β (Acetyl Lys72)

Concentration:

1 mg/ml

Molecular weight:

36850

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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