Background:

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus| cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants| encoding different isoforms| have been characterized.

Classification:

Primary antibody

Alternative names:

DISC1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DISC1

Concentration:

1 mg/ml

Molecular weight:

93940

Applications:

WB

Storage:

-20°C for 1 year

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