Background:

DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. This gene encodes a DEAD box protein| which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA| folds single-stranded RNA| and may play important roles in ribosomal RNA biogenesis| RNA editing| RNA transport| and general transcription.

Classification:

Primary antibody

Alternative names:

DDX21

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DDX21

Concentration:

1 mg/ml

Molecular weight:

86130

Applications:

WB

Storage:

-20°C for 1 year

More info:

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