Background:

The erythroid-specific protein encoded by this gene| and the ubiquitous transcription factor CP2| form the stage selector protein (SSP) complex| which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon| and a downstream AUG codon| results in two isoforms. While the long isoform (22 kDa) acts as an activator| the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand.

Classification:

Primary antibody

Alternative names:

NF-E4; Transcription factor NF-E4

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human NF-E4

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, WB

Storage:

-20°C for 1 year

More info:

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