Background:

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short| processed peptide molecules that are classified by structure into three groups: alpha-defensins| beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli| S. aureus| and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS)| a factor involved in inflammatory diseases and male reproductive issues.

Classification:

Primary antibody

Alternative names:

DB114

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DB114

Concentration:

1 mg/ml

Molecular weight:

7590

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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