Background:

DAD1| the defender against apoptotic cell death| was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature| suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme| thus reflecting the essential nature of N-linked glycosylation in eukaryotes.

Classification:

Primary antibody

Alternative names:

DAD1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human DAD1

Concentration:

1 mg/ml

Molecular weight:

12430

Applications:

WB

Storage:

-20°C for 1 year

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