Background:

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice| the disabled-1 gene plays a central role in brain development| directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1| and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported| but their full length nature has not been determined.

Classification:

Primary antibody

Alternative names:

Dab1 ;Tyr220; Disabled homolog 1

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phosho peptide around human Dab1 (Tyr220)

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

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