Background:

The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.|Adapter molecule functioning in neural development. May regulate SIAH1 activity.|PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.|Contains 1 PID domain.|subunit:Associates with the SH2 domains of SRC| FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.|

Classification:

Primary antibody

Alternative names:

Dab1 ;Phospho Tyr220; Disabled homolog 1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human Dab1 (Phospho Tyr220)

Concentration:

1 mg/ml

Molecular weight:

64680

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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