Background:

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants| encoding different isoforms| have been characterized.

Classification:

Primary antibody

Alternative names:

Insulin-like growth factor-binding protein 3; IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human IGFBP-3 around the phosphorylation site of Ser183. AA range:151-200

Concentration:

1 mg/ml

Molecular weight:

31674

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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