Background:

This gene encodes a cytokine that belongs to the interferon family of signaling proteins| which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons| which are important for defense against viral infections. In addition| type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen| type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.

Classification:

Primary antibody

Alternative names:

Interferon beta ;IFN-beta;Fibroblast interferon; Interferon beta; IFN-beta; Fibroblast interferon

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 91-140

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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