Background:

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex| which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

CRY2

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human CRY2

Concentration:

1 mg/ml

Molecular weight:

65230

Applications:

WB

Storage:

-20°C for 1 year

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