Background:

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain| an SH3-binding proline-rich region| and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

SH3 domain-binding protein 2 ;3BP-2

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 210-290

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

More info:

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