Background:

This gene encodes a member of the intermediate filament family. Intermediate filamentents| along with microtubules and actin microfilaments| make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape| integrity of the cytoplasm| and stabilizing cytoskeletal interactions. It is also involved in the immune response| and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment| migration| and cell signaling. Mutations in this gene causes a dominant| pulverulent cataract.

Classification:

Primary antibody

Alternative names:

vimentin; VIM

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)

Concentration:

1 mg/ml

Molecular weight:

51260

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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