Background:

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor| known as kinase insert domain receptor| is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation| survival| migration| tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors| including Rab GTPase| P2Y purine nucleotide receptor| integrin alphaVbeta3| T-cell protein tyrosine phosphatase| etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Classification:

Primary antibody

Alternative names:

VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 1268-1341

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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