Background:

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin| and also interacts with 5-lipoxygenase| which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region| the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

Classification:

Primary antibody

Alternative names:

COTL1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human COTL1

Concentration:

1 mg/ml

Molecular weight:

15620

Applications:

WB

Storage:

-20°C for 1 year

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