Background:

This gene is a member of the inhibitor of apoptosis (IAP) gene family| which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains| but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors| yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Baculoviral IAP repeat-containing protein 5; BIRC5; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Survivin. AA range:11-60

Concentration:

1 mg/ml

Molecular weight:

16389

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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