Background:

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Classification:

Primary antibody

Alternative names:

Signal transducing adapter molecule 2; STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human STAM2 around the phosphorylation site of Tyr192. AA range:161-210

Concentration:

1 mg/ml

Molecular weight:

58164

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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