Background:

This gene encodes a member of the epidermal growth factor (EGF)- Cripto| Frl-1| and Cryptic (CFC) family| which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif| a conserved cysteine-rich domain| and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development| including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Classification:

Primary antibody

Alternative names:

CFC1

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human CFC1

Concentration:

1 mg/ml

Molecular weight:

24530

Applications:

WB

Storage:

-20°C for 1 year

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