Background:

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage| this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Classification:

Primary antibody

Alternative names:

Proliferating cell nuclear antigen; PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin

Species reactivity:

Human, Mouse, Rat, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PCNA. AA range:61-110

Concentration:

1 mg/ml

Molecular weight:

28769

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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