Background:

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors| and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele)| supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene| but the biological validity and the full-length nature of some variants have not been determined.

Classification:

Primary antibody

Alternative names:

Tumor protein p73; TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human p73 around the phosphorylation site of Tyr99. AA range:66-115

Concentration:

1 mg/ml

Molecular weight:

69623

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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