Background:

DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure| such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. This gene encodes a DEAD box protein| which is a RNA-dependent ATPase| and also a proliferation-associated nuclear antigen| specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Probable ATP-dependent RNA helicase DDX5; DDX5; G17P1; HELR; HLR1; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5 around the phosphorylation site of Tyr593. AA range:565-614

Concentration:

1 mg/ml

Molecular weight:

69148

Applications:

WB, IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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