Background:

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation| preventing this transition to mitosis.

Classification:

Primary antibody

Alternative names:

Nuclear-interacting partner of ALK; ZC3HC1; NIPA; HSPC216; Nuclear-interacting partner of ALK; Nuclear-interacting partner of anaplastic lymphoma kinase; hNIPA; Zinc finger C3HC-type protein 1

Species reactivity:

Human, Mouse, Rat, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NIPA around the phosphorylation site of Ser354. AA range:320-369

Concentration:

1 mg/ml

Molecular weight:

55262

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for 1 year

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