Background:

This gene encodes a soluble| cytoplasmic| tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic| postlingual| progressive sensorineural DFNA44 hearing loss. In mouse| the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Classification:

Primary antibody

Alternative names:

CCD50

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human CCD50

Concentration:

1 mg/ml

Molecular weight:

33660

Applications:

WB

Storage:

-20°C for 1 year

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