Background:

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain| consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III)| is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development| including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia| retardation| aphasia| spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants| some of which include an alternate exon that is considered to be specific to neurons.

Classification:

Primary antibody

Alternative names:

Neural cell adhesion molecule L1; L1CAM; CAML1; MIC5; Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CD171/N-CAML1 around the phosphorylation site of Ser1181. AA range:1147-1196

Concentration:

1 mg/ml

Molecular weight:

140003

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com