Background:

The ATPase Na+/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases| and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation| for sodium-coupled transport of a variety of organic and inorganic molecules| and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits| a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Sodium/potassium-transporting ATPase subunit alpha-1; ATP1A1; Sodium/potassium-transporting ATPase subunit alpha-1; Na;+/K;+ ATPase alpha-1 subunit; Sodium pump subunit alpha-1

Species reactivity:

Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1 around the phosphorylation site of Ser23. AA range:15-64

Concentration:

1 mg/ml

Molecular weight:

113054

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for 1 year

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