Background:

The protein encoded by this gene is a member of the dual specificity protein kinase family| which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases| also known as extracellular signal-regulated kinases (ERKs)| act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway| this kinase is involved in many cellular processes such as proliferation| differentiation| transcription regulation and development.

Classification:

Primary antibody

Alternative names:

Dual specificity mitogen-activated protein kinase kinase 1; MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MEK1 around the phosphorylation site of Thr286. AA range:252-301

Concentration:

1 mg/ml

Molecular weight:

43439

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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