Background:

This gene encodes an anti-apoptotic protein| which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Classification:

Primary antibody

Alternative names:

Induced myeloid leukemia cell differentiation protein Mcl-1; MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EAT

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MCL1 around the phosphorylation site of Ser159. AA range:125-174

Concentration:

1 mg/ml

Molecular weight:

37337

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for 1 year

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