Background:

The product of this gene is a core component of the exon junction complex (EJC)| a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm| but shuttles into the nucleus where it localizes to nuclear speckles.

Classification:

Primary antibody

Alternative names:

CASC3

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human CASC3

Concentration:

1 mg/ml

Molecular weight:

77330

Applications:

WB

Storage:

-20°C for 1 year

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