Background:

Endogenous opioid peptides and opiates| like morphine| transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor| mu-type| delta-type and kappa-type| also designated MOR-1| DOR-1 and KOR-1| respectively. MOR-1 is a receptor for beta-endorphin| DOR-1 is a receptor for enkephalins| and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions| including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Classification:

Primary antibody

Alternative names:

Kappa-type opioid receptor; OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1

Species reactivity:

Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from mouse KOR-1 around the phosphorylation site of Ser369. AA range:331-380

Concentration:

1 mg/ml

Molecular weight:

42645

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com