Background:

This protein is highly similar to FLASH| a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor| Fas-binding adapter FADD| and caspase 8| and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Classification:

Primary antibody

Alternative names:

C8AP2

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human C8AP2

Concentration:

1 mg/ml

Molecular weight:

218020

Applications:

WB

Storage:

-20°C for 1 year

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